Avermectin B1a, a paralyzing anthelmintic that affects interneurons and inhibitory motoneurons in Ascaris.
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منابع مشابه
Identification of excitatory and inhibitory motoneurons in the nematode Ascaris by electrophysiological techniques.
A physiological preparation in which it is possible to record responses in muscle to stimulation of single motoneurons of the nematode Ascaris lumbricoides is described. With this preparation we have determined the physiological sign (E or I; excitatory or inhibitory) of the neuromuscular synapses of 21 identified motoneurons--12 are excitatory and 9 inhibitory. Ascaris motoneurons had previous...
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The interactions of the anthelmintic agent avermectin B1a, the anticonvulsant pentobarbital, and the anxiolytic tracazolate with the gamma-aminobutyric acid (GABA) receptor . chloride ion channel complex in rat brain membrane were studied. The results indicated that they all potentiated ligand binding to the GABA and benzodiazepine receptors. The stimulatory effects of avermectin B1a and pentob...
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Heavy-ion irradiation technology has advantages over traditional methods of mutagenesis. Heavy-ion irradiation improves the mutation rate, broadens the mutation spectrum, and shortens the breeding cycle. However, few data are currently available regarding its effect on Streptomyces avermitilis morphology and productivity. In this study, the influence of heavy-ion irradiation on S. avermitilis w...
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at least on the lower surface, rarely glabrous; petioles ? ^ in. Bracteoles \ in., narrow?lanceolate, somewhat persistent. Panicles terminal, the racemes densely fulvous-villous, and congested. Ovary-sessile, young fulvous-villous. Calyx shortly constricted above the ovary then funnelshaped, hairy within and without; calyx-tube upwards 5-fluted, the segments triangular, acute, erect. Petals nar...
متن کاملInhibitory interneurons and network oscillations.
N euronal networks in the brain oscillate in various frequency bands, and such oscillations can be detected by observing local field potential or EEG activity (1). Oscillations in the gamma frequency band (30–80 Hz) have drawn special attention because of their link to a variety of cognitive processes including sensory binding (2), attention selection (3), and memory (4, 5). Of particular physi...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1980
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.77.10.6211